Speaker: Niel Hens
Thời gian: 18h00, Thứ 4, ngày 9/12/2015
Địa điểm: Phòng 201, Nhà A5, Viện Toán học, 18 Hoàng Quốc Việt, Cầu Giấy, Hà Nội
Tóm tắt: In the past three decades, vaccine policy has become increasingly informed by the use of cross-sectional serosurvey collections that provide estimates of population immunity. Such studies rely on the assumption that the antibody test correlates well with the level of immunity. Uses of such data include monitoring of the immune status of populations and informing transmission modeling studies, through estimation of the pre-vaccination force of infection and the basic reproduction number in assessments of new vaccine programs. Another important use is in model validation, or in improving estimates of model parameters. In recent years, however, there has been considerable development in both the methods used in estimating parameters from sero-survey data and the range of questions that can be asked of such data. Using (series of) cross-sectional serosurvey(s) in which multiple antigens were tested two topics will addressed: estimating vaccine coverage and unravelling different sources of heterogeneity in acquisition of infection. |
